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1

Clinical whole exome sequencing in severe hypertriglyceridemia

Tada, Hayato, Nomura, Akihiro, Okada, Hirofumi, Nakahashi, Takuya, Nozue, Tsuyoshi, Hayashi, Kenshi, Nohara, Atsushi, Yagi, Kunimasa, Inazu, Akihiro, Michishita, Ichiro, Mabuchi, Hiroshi, Yamagishi, M

Journal:

Clinica Chimica Acta

Year:

2019

Language:

english

File:

PDF, 1.37 MB

english, 2019

2

Effects of CoQ10 supplementation on plasma lipoprotein lipid, CoQ10 and liver and muscle enzyme levels in hypercholesterolemic patients treated with atorvastatin: A randomized double-blind study

Hiroshi Mabuchi, Atsushi Nohara, Junji Kobayashi, Masa-aki Kawashiri, Shoji Katsuda, Akihiro Inazu, Junji Koizumi

Journal:

Atherosclerosis

Year:

2007

Language:

english

File:

PDF, 292 KB

english, 2007

3

Postprandial lipoprotein metabolism: VLDL vs chylomicrons

Katsuyuki Nakajima, Takamitsu Nakano, Yoshiharu Tokita, Takeaki Nagamine, Akihiro Inazu, Junji Kobayashi, Hiroshi Mabuchi, Kimber L. Stanhope, Peter J. Havel, Mitsuyo Okazaki, Masumi Ai, Akira Tanaka

Journal:

Clinica Chimica Acta

Year:

2011

Language:

english

File:

PDF, 1.20 MB

english, 2011

4

Reduction of Serum Ubiquinol-10 and Ubiquinone-10 Levels by Atorvastatin in Hypercholesterolemic Patients

Mabuchi, Hiroshi, Higashikata, Toshinori, Kawashiri, Masaaki, Katsuda, Shoji, Mizuno, Mihoko, Nohara, Atsushi, Inazu, Akihiro, Koizumi, Junji, Kobayashi, Junji

Journal:

Journal of Atherosclerosis and Thrombosis

Year:

2005

Language:

english

File:

PDF, 151 KB

english, 2005

5

Changes in lipoprotein lipase and endothelial lipase mass in familial hypercholesterolemia during three-drug lipid-lowering combination therapy

Tada, Hayato, Kobayashi, Junji, Kawashiri, Masa-aki, Miyashita, Kazuya, Nohara, Atsushi, Inazu, Akihiro, Nakajima, Katsuyuki, Mabuchi, Hiroshi, Yamagishi, Masakazu

Journal:

Lipids in Health and Disease

Year:

2016

Language:

english

File:

PDF, 1.11 MB

english, 2016

6

A novel method for determining functional LDL receptor activity in familial hypercholesterolemia: Application of the CD3/CD28 assay in lymphocytes

Hayato Tada, Masa-aki Kawashiri, Tohru Noguchi, Mika Mori, Masayuki Tsuchida, Mutsuko Takata, Atsushi Nohara, Akihiro Inazu, Junji Kobayashi, Akihiro Yachie, Hiroshi Mabuchi, Masakazu Yamagishi

Journal:

Clinica Chimica Acta

Year:

2009

Language:

english

File:

PDF, 591 KB

english, 2009

7

P-214 Clinical Impact of Heterozygous Carrier of Autosomal Recessive Hypercholesterolemia on Asymptomatic Hyperlipidemic Patients

Hayato Tada, Masa-aki Kawashiri, Tohru Noguchi, Chiaki Nakanishi, Masayuki Tsuchida, Mutsuko Takata, Atsushi Nohara, Akihiro Inazu, Junji Kobayashi, Hiroshi Mabuchi, Masakazu Yamagishi

Journal:

CVD Prevention and Control

Year:

2009

Language:

english

File:

PDF, 50 KB

english, 2009

8

Assessment of arterial stiffness in patients with familial hypercholesterolemia

Tada, Hayato, Kawashiri, Masa-aki, Nohara, Atsushi, Inazu, Akihiro, Mabuchi, Hiroshi, Yamagishi, Masakazu

Journal:

Journal of Clinical Lipidology

Year:

2017

Language:

english

File:

PDF, 353 KB

english, 2017

9

Effects of serum B vitamins on elevated plasma homocysteine levels associated with the mutation of methylenetetrahydrofolate reductase gene in Japanese

Yuri Moriyama, Tomonori Okamura, Kouji Kajinami, Hiroyasu Iso, Akihiro Inazu, Masaaki Kawashiri, Mihoko Mizuno, Yoshiko Takeda, Yasuki Sakamoto, Humio Kimura, Hideyoshi Suzuki, Hiroshi Mabuchi

Journal:

Atherosclerosis

Year:

2002

Language:

english

File:

PDF, 122 KB

english, 2002

10

Opposite effects on serum cholesteryl ester transfer protein levels between long-term treatments with pravastatin and probucol in patients with primary hypercholesterolemia and xanthoma

Akihiro Inazu, Junji Koizumi, Kouji Kajinami, Tsuyoshi Kiyohar, Kenji Chichibu, Hiroshi Mabuchi

Journal:

Atherosclerosis

Year:

1999

Language:

english

File:

PDF, 115 KB

english, 1999

11

LIPOPROTEIN(A) IN FAMILIAL HYPERCHOLESTEROLEMIA WITH PCSK9 GAIN-OF-FUNCTION MUTATIONS

Tada, Hayato, Kawashiri, Masa-Aki, Nohara, Atsushi, Inazu, Akihiro, Mabuchi, Hiroshi, Yamagishi, Masakazu

Journal:

Journal of the American College of Cardiology

Year:

2016

Language:

english

File:

PDF, 341 KB

english, 2016

12

Common functional variant LIPA T16P affects HDL composition among patients with heterozygous familial hypercholesterolemia

Nohara, Atushi, Kawashiri, Masa-Aki, Eto, Yoshikatsu, Fujisaki, Miwa, Tada, Hayato, Yoshida, Mie, Mori, Mika, Nakanishi, Chiaki, Yagi, Kunimasa, Inazu, Akihiro, Yamagishi, Masakazu, Mabuchi, Hiroshi

Journal:

Atherosclerosis

Year:

2017

Language:

english

File:

PDF, 590 KB

english, 2017

13

Effect of common methylenetetrahydrofolate reductase gene mutation on coronary artery disease in familial hypercholesterolemia

Masa-aki Kawashiri, Kouji Kajinami, Atsushi Nohara, Kunimasa Yagi, Akihiro Inazu, Junji Koizumi, Hiroshi Mabuchi

Journal:

The American Journal of Cardiology

Year:

2000

Language:

english

File:

PDF, 171 KB

english, 2000

14

A 4-year trial of simvastatin in the treatment of patients with heterozygous familial hypercholesterolemia

Masako Kitatani, Junji Koizumi, Akihiro Inazu, Kouji Kajinami, Hiroshi Mabuchi

Journal:

Current Therapeutic Research

Year:

1996

Language:

english

File:

PDF, 614 KB

english, 1996

15

A novel type of familial hypercholesterolemia: Double heterozygous mutations in LDL receptor and LDL receptor adaptor protein 1 gene

Hayato Tada, Masa-aki Kawashiri, Rumiko Ohtani, Tohru Noguchi, Chiaki Nakanishi, Tetsuo Konno, Kenshi Hayashi, Atsushi Nohara, Akihiro Inazu, Junji Kobayashi, Hiroshi Mabuchi, Masakazu Yamagishi

Journal:

Atherosclerosis

Year:

2011

Language:

english

File:

PDF, 192 KB

english, 2011

16

Identification of Two Novel Missense Mutations (p.R1221C and p.R1357W) in the ABCC6 (MRP6) Gene in a Japanese Patient with Pseudoxanthoma Elasticum (PXE)

NOJI, Yoshihiro, INAZU, Akihiro, HIGASHIKATA, Toshinori, NOHARA, Atsushi, KAWASHIRI, Masa-aki, YU, Wenxin, TODO, Yasuhiro, NOZUE, Tsuyoshi, UNO, Yoshihide, HIFUMI, Senshu, MABUCHI, Hiroshi

Journal:

Internal Medicine

Year:

2004

Language:

english

File:

PDF, 147 KB

english, 2004

17

Haplotype analyses of cholesteryl ester transfer protein gene promoter: a clue to an unsolved mystery ofTaqIB polymorphism

Hong Lu, Akihiro Inazu, Yuri Moriyama, Toshinori Higashikata, Masa-aki Kawashiri, Wenxin Yu, Zhiping Huang, Tomonori Okamura, Hiroshi Mabuchi

Journal:

Journal of Molecular Medicine

Year:

2003

Language:

english

File:

PDF, 239 KB

english, 2003

18

Alternative splicing of the mRNA encoding the human cholesteryl ester transfer protein

Inazu, Akihiro, Quinet, Elaine M., Wang, Suke, Brown, Maryanne L., Stevenson, Susan, Barr, Mark L., Moulin, Philippe, Tall, Alan R.

Journal:

Year:

1992

Language:

english

File:

PDF, 1.83 MB

english, 1992

19

Dual effects on HDL metabolism by cholesteryl ester transfer protein inhibition in HepG2 cells

Huang, Zhiping, Inazu, Akihiro, Kawashiri, Masa-aki, Nohara, Atsushi, Higashikata, Toshinori, Mabuchi, Hiroshi

Journal:

American Journal of Physiology-Endocrinology and Metabolism

Year:

2003

Language:

english

File:

PDF, 272 KB

english, 2003

20

Compound heterozygote of cholesteryl-ester transfer protein deficiency in a patient with hyperalphalipoproteinemia

Tadayoshi Takegoshi, Toshihiro Haba, Chikashi Kitoh, Akihiro Inazu, Junji Koizumi, Hiroshi Mabuchib, Ryoyu Takeda

Journal:

Atherosclerosis

Year:

1992

Language:

english

File:

PDF, 198 KB

english, 1992

21

The HDL Handbook || Cholesteryl Ester Transfer Protein Inhibitors

Year:

2014

Language:

english

File:

PDF, 599 KB

english, 2014

22

LIPOPROTEIN(A) IN FAMILIAL HYPERCHOLESTEROLEMIA WITH PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 GAIN-OF-FUNCTION MUTATIONS: IMPLICATION OF RESIDUAL RISK IN STATIN-ERA

Tada, Hayato, Kawashiri, Masa-aki, Nohara, Atsushi, Inazu, Akihiro, Mabuchi, Hiroshi, Yamagishi, Masakazu

Journal:

Journal of the American College of Cardiology

Year:

2015

Language:

english

File:

PDF, 233 KB

english, 2015

23

Removal of apolipoprotein E-enriched high density lipoprotein by LDL-apheresis in familial hypercholesterolaemia: a possible activation of the reverse cholesterol transport system

Junji Koizumi, Akihiro Inazu, Hajime Fujita, Mitsuaki Takeda, Yoshihide Uno, Kouji Kajinami, Hiroshi Mabuchi, Ryoyu Takeda

Journal:

Atherosclerosis

Year:

1988

Language:

english

File:

PDF, 1.08 MB

english, 1988

24

Whole exome sequencing combined with integrated variant annotation prediction identifies asymptomatic Tangier disease with compound heterozygous mutations in ABCA1 gene

Tada, Hayato, Kawashiri, Masa-aki, Nohara, Atsushi, Saito, Reina, Tanaka, Yoshihiro, Nomura, Akihiro, Konno, Tetsuo, Sakata, Kenji, Fujino, Noboru, Takamura, Toshinari, Inazu, Akihiro, Mabuchi, Hirosh

Journal:

Atherosclerosis

Year:

2015

Language:

english

File:

PDF, 686 KB

english, 2015

25

Marked Aortic Valve Stenosis Progression After Receiving Long-Term Aggressive Cholesterol-Lowering Therapy Using Low-Density Lipoprotein Apheresis in a Patient With Familial Hypercholesterolemia

Tsuchida, Masayuki, Kawashiri, Masa-aki, Tada, Hayato, Takata, Mutsuko, Nohara, Atsushi, Ino, Hidekazu, Inazu, Akihiro, Kobayashi, Junji, Koizumi, Junji, Mabuchi, Hiroshi, Yamagishi, Masakazu

Journal:

Circulation Journal

Year:

2009

Language:

english

File:

PDF, 397 KB

english, 2009

26

Autosomal Recessive Hypercholesterolemia: A Mild Phenotype of Familial Hypercholesterolemia: Insight from the Kinetic Study using Stable Isotope and Animal Studies

Tada, Hayato, Kawashiri, Masa-aki, Nohara, Atsushi, Inazu, Akihiro, Kobayashi, Junji, Mabuchi, Hiroshi, Yamagishi, Masakazu

Journal:

Journal of Atherosclerosis and Thrombosis

Year:

2015

Language:

english

File:

PDF, 1.44 MB

english, 2015

27

Apolipoprotein B gene mutations and fatty liver in Japanese hypobetalipoproteinemia

Shoji Katsuda, Masa-aki Kawashiri, Akihiro Inazu, Hayato Tada, Masayuki Tsuchida, Yoshibumi Kaneko, Tsuyoshi Nozue, Atsushi Nohara, Toshihide Okada, Junji Kobayashi, Ichiro Michishita, Hiroshi Mabuchi

Journal:

Clinica Chimica Acta

Year:

2009

Language:

english

File:

PDF, 404 KB

english, 2009

28

Additive effects of another kind of HMG-CoA reductase inhibitor with different pharmacokinetics in the treatment of heterozygous familial hypercholesterolemia

Tsuyoshi Nozue, Atsushi Nohara, Toshinori Higashikata, Akihiro Inazu, Hiroshi Mabuchi, Kouji Kajinami, Junji Koizumi

Journal:

Atherosclerosis

Year:

2000

Language:

english

File:

PDF, 49 KB

english, 2000

29

Cholesteryl ester transfer protein and atherosclerosis

Inazu, Akihiro, Koizumi, Junji, Mabuchi, Hiroshi

Journal:

Current Opinion in Lipidology

Year:

2000

Language:

english

File:

PDF, 193 KB

english, 2000

30

Molecular basis of lipid transfer protein deficiency in a family with increased high-density lipoproteins

Brown, Maryanne L., Inazu, Akihiro, Hesler, Charles B., Agellon, Luis B., Mann, Chris, Whitlock, Mary E., Marcel, Yves L., Milne, Ross W., Koizumi, Junji, Mabuchi, Hiroshi

Journal:

Year:

1989

File:

PDF, 517 KB

1989

31

Novel mutations of cholesteryl ester transfer protein (CETP) gene in Japanese hyperalphalipoproteinemic subjects

Rumiko Ohtani, Akihiro Inazu, Yoshihiro Noji, Takanobu Wakasugi, Kenji Miwa, Hayato Tada, Masa-aki Kawashiri, Tohru Noguchi, Atsushi Nohara, Junji Kobayashi, Junji Koizumi, Masakazu Yamagishi, Hiroshi

Journal:

Clinica Chimica Acta

Year:

2012

Language:

english

File:

PDF, 1.05 MB

english, 2012

32

Circulating Matrix Metalloproteinases and Their Inhibitors in Premature Coronary Atherosclerosis

Noji, Yoshihiro, Kajinami, Kouji, Kawashiri, Masa-aki, Todo, Yasuhiro, Horita, Takahiro, Nohara, Atsushi, Higashikata, Toshinori, Inazu, Akihiro, Koizumi, Junji, Takegoshi, Tadayoshi, Mabuchi, Hiroshi

Journal:

Clinical Chemistry and Laboratory Medicine

Year:

2001

Language:

english

File:

PDF, 291 KB

english, 2001

33

Cholesteryl Ester Transfer Protein (CETP) Deficiency and CETP Inhibitors

Mabuchi, Hiroshi, Nohara, Atsushi, Inazu, Akihiro

Journal:

Molecules and Cells

Year:

2014

Language:

english

File:

PDF, 502 KB

english, 2014

34

Assessments of Carotid Artery Plaque Burden in Patients With Familial Hypercholesterolemia

Tada, Hayato, Kawashiri, Masa-aki, Okada, Hirofumi, Nakahashi, Takuya, Sakata, Kenji, Nohara, Atsushi, Inazu, Akihiro, Mabuchi, Hiroshi, Yamagishi, Masakazu, Hayashi, Kenshi

Journal:

The American Journal of Cardiology

Year:

2017

Language:

english

File:

PDF, 574 KB

english, 2017

35

Post-prandial Remnant Lipoprotein Metabolism in Sitosterolemia

Tada, Hayato, Nomura, Akihiro, Nohara, Atsushi, Inazu, Akihiro, Mabuchi, Hiroshi, Yamagishi, Masakazu, Kawashiri, Masa-aki

Journal:

Journal of Atherosclerosis and Thrombosis

Year:

2018

Language:

english

File:

PDF, 846 KB

english, 2018

36

Serum lipoprotein lipase mass: Clinical significance of its measurement

Junji Kobayashi, Atsushi Nohara, Masa-aki Kawashiri, Akihiro Inazu, Junji Koizumi, Katsuyuki Nakajima, Hiroshi Mabuchi

Journal:

Clinica Chimica Acta

Year:

2007

Language:

english

File:

PDF, 183 KB

english, 2007

37

Reduction of lipoprotein(a) by LDL-apheresis using a dextran sulfate cellulose column in patients with familial hypercholesterolemia

Junji Koizumi, Ichiro Koizumi, Yoshihide Uno, Akihiro Inazu, Kouvi Kajinami, Tatsuo Haraki, Kunimasa Yagi, Nobuo Kamon, Susumu Miyamoto, Tadayoshi Takegoshi, Hiroshi Mabuchi, Ryoyu Takeda, Nobutaka Ta

Journal:

Atherosclerosis

Year:

1993

Language:

english

File:

PDF, 898 KB

english, 1993

38

Comparison of effects of bezafibrate and fenofibrate on circulating proprotein convertase subtilisin/kexin type 9 and adipocytokine levels in dyslipidemic subjects with impaired glucose tolerance or type 2 diabetes mellitus: Results from a crossover study

Tohru Noguchi, Junji Kobayashi, Kunimasa Yagi, Atsushi Nohara, Naoto Yamaaki, Masako Sugihara, Naoko Ito, Rie Oka, Masa-aki Kawashiri, Hayato Tada, Mutsuko Takata, Akihiro Inazu, Masakazu Yamagishi, H

Journal:

Atherosclerosis

Year:

2011

Language:

english

File:

PDF, 165 KB

english, 2011

39

Molecular Genetics of Cholesterol Transport and Cholesterol Reverse Transport Disorders (Familial Hypercholesterolemia and CETP Deficiency) and Coronary Heart Disease

HIROSHI MABUCHI, KUNIMASA YAGI, TATSUO HARAKI, HIROYUKA MATSUSHITA, AKIHIRO INAZU, KOUJI KAJINAMI, JUNJI KOIZUMI

Journal:

Annals of the New York Academy of Sciences

Year:

1994

Language:

english

File:

PDF, 467 KB

english, 1994

40

Plasma homocysteine level and development of coronary artery disease

Kawashiri, Masa-aki, Kajinami, Kouji, Nohara, Atsushi, Yagi, Kunimasa, Inazu, Akihiro, Koizumi, Junji, Haraki, Tatsuo, Takegoshi, Tadayoshi, Mabuchi, Hiroshi

Journal:

Coronary Artery Disease

Year:

1999

File:

PDF, 411 KB

1999

41

Sitosterolemia, Hypercholesterolemia, and Coronary Artery Disease

Tada, Hayato, Nohara, Atsushi, Inazu, Akihiro, Sakuma, Nagahiko, Mabuchi, Hiroshi, Kawashiri, Masa-aki

Journal:

Journal of Atherosclerosis and Thrombosis

Year:

2018

Language:

english

File:

PDF, 1.83 MB

english, 2018

42

The distribution of fasting and non-fasting serum triglyceride levels in Japanese population

Junji Kobayashi, Atsushi Nohara, Masa-aki Kawashiri, Osamu Miyazaki, Akihiro Inazu, Hiroshi Mabuchi, Masaji Tabata

Journal:

Clinica Chimica Acta

Year:

2006

Language:

english

File:

PDF, 179 KB

english, 2006

43

Impact of bezafibrate and atorvastatin on lipoprotein subclass in patients with type III hyperlipoproteinemia: Result from a crossover study

Masa-aki Kawashiri, Junji Kobayashi, Atsushi Nohara, Tohru Noguchi, Hayato Tada, Chiaki Nakanishi, Akihiro Inazu, Hiroshi Mabuchi, Masakazu Yamagishi

Journal:

Clinica Chimica Acta

Year:

2011

Language:

english

File:

PDF, 615 KB

english, 2011

44

Cholesteryl ester transfer protein inhibitors: new strategies for raising high-density lipoprotein cholesterol

Mabuchi, Hiroshi, Inazu, Akihiro

Journal:

Future Lipidology

Year:

2006

Language:

english

File:

PDF, 3.31 MB

english, 2006

45

Efficacy of Colestimide Coadministered With Atorvastatin in Japanese Patients With Heterozygous Familial Hypercholesterolemia (FH)

Kawashiri, Masa-aki, Higashikata, Toshinori, Nohara, Atsushi, Kobayashi, Junji, Inazu, Akihiro, Koizumi, Junji, Mabuchi, Hiroshi

Journal:

Circulation Journal

Year:

2005

Language:

english

File:

PDF, 193 KB

english, 2005

46

Molecular and functional characterization of familial chylomicronemia syndrome

Teramoto, Ryota, Tada, Hayato, Kawashiri, Masa-aki, Nohara, Atsushi, Nakahashi, Takuya, Konno, Tetsuo, Inazu, Akihiro, Mabuchi, Hiroshi, Yamagishi, Masakazu, Hayashi, Kenshi

Journal:

Atherosclerosis

Year:

2017

Language:

english

File:

PDF, 907 KB

english, 2017

47

Efficacy and Safety of Coadministration of Rosuvastatin, Ezetimibe, and Colestimide in Heterozygous Familial Hypercholesterolemia

Masa-aki Kawashiri, Atsushi Nohara, Tohru Noguchi, Hayato Tada, Chiaki Nakanishi, Mika Mori, Tetsuo Konno, Kenshi Hayashi, Noboru Fujino, Akihiro Inazu, Junji Kobayashi, Hiroshi Mabuchi, Masakazu Yama

Journal:

The American Journal of Cardiology

Year:

2012

Language:

english

File:

PDF, 487 KB

english, 2012

48

Serum lipoprotein lipid concentration and composition in homozygous and heterozygous patients with cholesteryl ester transfer protein deficiency

Junji Koizumi, Akihiro Inazu, Kunimasa Yagi, Ichiro Koizumi, Yoshihide Uno, Kouji Kajinami, Susumu Miyamoto, Philippe Moulin, Alan R. Tall, Hiroshi Mabuchi, Ryoyu Takeda

Journal:

Atherosclerosis

Year:

1991

Language:

english

File:

PDF, 688 KB

english, 1991

49

Remnant-like particles and coronary artery disease in familial hypercholesterolemia

Tada, Hayato, Kawashiri, Masa-aki, Nohara, Atsushi, Sakata, Kenji, Inazu, Akihiro, Mabuchi, Hiroshi, Yamagishi, Masakazu, Hayashi, Kenshi

Journal:

Clinica Chimica Acta

Year:

2018

Language:

english

File:

PDF, 268 KB

english, 2018

50

Post-prandial remnant lipoprotein metabolism in autosomal recessive hypercholesterolaemia

Hayato Tada, Masa-aki Kawashiri, Akira Tanaka, Takamitsu Nakano, Katsuyuki Nakajima, Takeshi Inoue, Tohru Noguchi, Chiaki Nakanishi, Tetsuo Konno, Kenshi Hayashi, Atsushi Nohara, Akihiro Inazu, Junji

Journal:

European Journal of Clinical Investigation

Year:

2012

Language:

english

File:

PDF, 247 KB

english, 2012

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